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Alexander I Spira Selected Research

amivantamab-vmjw

2/2022MARIPOSA: phase 3 study of first-line amivantamab + lazertinib versus osimertinib in EGFR-mutant non-small-cell lung cancer.
10/2021Amivantamab in EGFR Exon 20 Insertion-Mutated Non-Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results From the CHRYSALIS Phase I Study.

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Alexander I Spira Research Topics

Disease

15Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
02/2022 - 12/2009
8Neoplasms (Cancer)
12/2021 - 08/2003
3Fatigue
12/2021 - 01/2012
2Lung Neoplasms (Lung Cancer)
12/2021 - 10/2019
2Sarcoma (Soft Tissue Sarcoma)
01/2021 - 01/2002
2Neutropenia
01/2012 - 12/2009
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
02/2022
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2022
1Pruritus (Itching)
12/2021
1Nasopharyngeal Neoplasms (Cancer of the Nasopharynx)
12/2021
1Brain Neoplasms (Brain Tumor)
12/2021
1Melanoma (Melanoma, Malignant)
10/2021
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2020
1Carcinoma (Carcinomatosis)
01/2020
1Heart Diseases (Heart Disease)
10/2019
1Inflammation (Inflammations)
10/2019
1Neoplasm Metastasis (Metastasis)
10/2019
1Ovarian Neoplasms (Ovarian Cancer)
06/2017
1Disease Progression
01/2017
1Exanthema (Rash)
01/2017
1Diarrhea
01/2017
1Adenocarcinoma
09/2013
1Pain (Aches)
02/2013
1Prostatic Neoplasms (Prostate Cancer)
02/2013
1Nausea
01/2012
1Anemia
01/2012
1Alopecia (Baldness)
01/2012

Drug/Important Bio-Agent (IBA)

4PlatinumIBA
01/2022 - 06/2017
3ErbB Receptors (EGF Receptor)IBA
10/2021 - 01/2017
2amivantamab-vmjwIBA
02/2022 - 10/2021
2GemcitabineFDA Link
01/2022 - 01/2021
2RNA (Ribonucleic Acid)IBA
12/2021 - 08/2019
2Tyrosine Kinase InhibitorsIBA
10/2021 - 02/2013
2NivolumabIBA
10/2021 - 01/2021
2Pharmaceutical PreparationsIBA
01/2017 - 01/2012
1lazertinibIBA
02/2022
1osimertinibIBA
02/2022
1Phosphotransferases (Kinase)IBA
02/2022
1B7-H1 AntigenIBA
01/2022
1berzosertibIBA
01/2022
1adagrasibIBA
01/2022
1VX (EDIM)IBA
01/2022
1Protein Kinase InhibitorsIBA
01/2022
1spartalizumabIBA
12/2021
1brigatinibIBA
12/2021
1CrizotinibIBA
12/2021
1bempegaldesleukinIBA
10/2021
1Interleukin-2 (IL2)IBA
10/2021
1Leucine (L-Leucine)FDA Link
01/2021
1pepinemabIBA
01/2021
1mobocertinibIBA
01/2021
1Immunoconjugates (Immunoconjugate)IBA
01/2021
1DV281IBA
01/2021
1avelumabIBA
01/2021
1Polo-Like Kinase 1IBA
12/2020
1onvansertibIBA
12/2020
1AlbuminsIBA
01/2020
1durvalumabIBA
01/2020
1Biomarkers (Surrogate Marker)IBA
01/2020
1Serum AlbuminIBA
01/2020
1Biological ProductsIBA
10/2019
1Proteins (Proteins, Gene)FDA Link
10/2019
1canakinumabFDA Link
10/2019
1CytokinesIBA
10/2019
1DNA (Deoxyribonucleic Acid)IBA
11/2018
1Cell-Free Nucleic AcidsIBA
11/2018
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2017
1Alanine Transaminase (SGPT)IBA
01/2017
1AfatinibIBA
01/2017
1Sunitinib (Sutent)FDA Link
10/2013
1Docetaxel (Taxotere)FDA Link
09/2013
1Oxaliplatin (Eloxatin)FDA LinkGeneric
09/2013
1Cetuximab (Erbitux)FDA Link
09/2013
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
02/2013
1Narcotics (Narcotic Analgesics)IBA
02/2013
1cabozantinibIBA
02/2013
1entinostat (MS 275)IBA
06/2012
1Erlotinib Hydrochloride (CP 358,774)FDA Link
06/2012
1taxaneIBA
01/2012
1eribulinFDA Link
01/2012
1Bevacizumab (Avastin)FDA Link
12/2009
1Albumin-Bound PaclitaxelFDA Link
12/2009
1Paclitaxel (Taxol)FDA LinkGeneric
12/2009
1Carboplatin (JM8)FDA LinkGeneric
12/2009
1130-nm albumin-bound paclitaxelIBA
12/2009

Therapy/Procedure

10Therapeutics
02/2022 - 08/2003
7Drug Therapy (Chemotherapy)
01/2022 - 01/2002
1Immunotherapy
01/2021
1Combination Drug Therapy (Combination Chemotherapy)
09/2013
1Castration
02/2013